Debuffs

Debuffs are status effects that affect the player or target negatively.

List of debuffs

From enemies

Icon	Name	Effect	Tooltip
	Anticoagulation	Lose 2 health per second, getting hit drops blood droplets that increase the damage of enemies who pick them up.	Losing life, shed blood when hurt, enemies will drink it and grow stronger
	Antisocial	Disables minions and pets, and reduces summon damage by 90%.	You have no friends and no summon damage
	Atrophied	Reduces melee damage by 99%, halved melee speed, and melee hits cannot critically strike.	Your muscles are deteriorating
	Berserked	Player constantly moves and uses item, increases damage and movement speed by 10%, and reduces damage reduction by 10%.	Increased offense, decreased defense, and you cannot control yourself
	Bloodthirsty	100x spawn rate and 3x max spawns.	Hugely increased enemy spawn rate
	Baron's Burden	Lose 45 health per second and gravity increased above water, improved swimming and unlimited breath underwater.	Gravity heavily increased outside water Breathe water but cannot breathe air Improved underwater movement
	Clipped Wings	Disables player wings and rocket boots, reduces enemy velocity and prevents them from traveling upwards.	You cannot fly or use rocket boots
	Crippled	Disables boot's sprint effect and halves movement speed.	You cannot run
	Curse of the Moon	Lose 10 health per second, decreases defense by 20, and decreases damage, critical strike chance, and damage reduction by 20%.	The moon's wrath consumes you
	Defenseless	Decreases defense by 30 and disables damage reduction, Beetle Endurance, knockback immunity, and invincibility frame boosts.	Your guard is completely broken
	Flames of the Universe	Lose 40 health per second, decreases defense by 15, and cannot regenerate life.	The heavens themselves have judged you
	Flipped	Reverses gravity.	Your gravity is reversed
	Fused	Causes the player to explode when the debuff expires.	You're going out with a bang
	God Eater	Lose 85 health per second, disables natural health regeneration, and reduces health regeneration by 70.	Your soul is cursed by divine wrath
	Guilty	Decreases damage by 25%.	Weapons dulled by the guilt of slaying innocent critters
	Hexed	Attacks heal enemies and deal no knockback.	Your attacks heal enemies
	Hypothermia	Cold enemy attacks deal 20% more damage.	Increased damage taken from cold attacks
	Infested	Lose health. As the duration ticks down, the damage becomes exponentially stronger.	This can only get worse
	Ivy Venom	Lose 30 health per second, the duration can stack and will become Neurotoxin at 20 seconds.	Losing life, will become Neurotoxin at 20 seconds
	Jammed	Ranged weapons shoot harmless confetti.	Your ranged weapons are faulty
	Lethargic	All item speed reduced to 75% speed.	Your weapons feel sluggish
	Lightning Rod	Spawns a Vortex Lightning once per second.	You attract thunderbolts
	Living Wasteland	Creates an aura that inflicts Rotting to Town NPCs.	Everyone around you turns to rot
	Lovestruck	Attacks spawns Hearts that heal Nymph and Deviantt when hitting them.	You are in love!
	Low Ground	Disables mounts and hooks, phases through platforms, and disables water walking effect.	No hooks, cannot stand on platforms or liquids
	Marked for Death	Takes 1.5x damage.	Just don't get hit
Midas (Eternity Mode)	Midas	Getting hit drops all coins.	Drop money on hit
	Mutant Nibble	Disables all health regeneration, Feral Bite and Moon Bite effects.	You cannot heal at all
	Nano Injection	Lose 5 health per second, reduces damage and movement speed by 10% and defense by 10.	Life regeneration and stats reduced
	Neurotoxin	Lose 32 health per second, greatly decreases movement speed.	Your body is shutting down
	Nullification Curse	Moon Lord only takes a certain damage type at a time.	Moon Lord has cycling damage type immunities!
	Oceanic Maul	Reduces maximum health, reduces defense by 10 and damage reduction by 10%, and Bleeding effect.	Defensive stats and max life are savaged
	Oiled	Takes double damage from all damage over time debuffs.	Taking more damage from being on fire
	Purged	Disables dodge, Gutted Heart, and Squeaky Toy effects.	Dodge effects don't work
	Purified	Removes all buffs except minions, mounts and pets.	You are cleansed
	Reverse Mana Flow	Magic attacks have halved speed, use health instead of mana, and heal enemies for 25% of their normal damage.	Your magic weapons cost life instead of mana
	Rotting	Moves with 0.9x speed, reduces defense by 10, attack speed and damage, and damage reduction by 10%.	Your body is wasting away
	Smite	Disables life regeneration, and takes 10% increased damage.	Life regen reduced and 20% more damage taken
	Shadowflame	Lose 5 health per second	Losing life
	Squeaky Toy	Attacks deal 1 damage and squeak.	Your attacks are squeaky toys!
	Stunned	Prevents the player from moving or using any items.	You're too dizzy to move
	Swarming	Hornets can move through tiles and approach the player faster.	Hornets are attacking from every direction!
	Time Frozen	Stops the player and projectiles in place.	You are stopped in time
	Unlucky	Reduces luck by 1.	You are feeling pretty unlucky
	Unstable	Randomly teleports to a nearby location once per second.	You don't quite fit into reality

From items and environment

Icon	Name	Effect	Tooltip
	Berserker Install	Massively increased offensive boosts, massively lowered defense and damage reduction, and the player cannot stop attacking or moving.	'Get them! Berserker!'
	Cerebral Mindbreak	30% decreased damage dealt.	30% decreased damage dealt
	Holy Price	30% decreased attack speed.	30% decreased attack speed
	Lihzahrd Curse	Disables Dangersense, and wires vision and placing.	Wires disabled in Jungle Temple
	Rush Job	Prevents the player from using Nurse's heal.	The Nurse cannot heal you again yet
	Twins Install	Effects of Cursed Inferno and Ichor.	Effects of Cursed Inferno and Ichor
	Snowstorm Cooldown	Prevents the use of the Snow or Frost Enchantment's ability to inflict chill on all enemies.	You cannot chill yet

From player

Icon	Name	Effect
	Corrupting	10% less contact damage, 10/30 less armor
	Hell Fire	Losing 100 health per second.
	Lead Poison	Losing 10 health per second.
	Orichalcum Poison	Losing 20 health per second.
Pungent Gaze	Pungent Gaze	Takes increased damage up to 15%
	Solar Flare	Losing 50 health per second, and creates an explosion when the debuff duration ended.

Notes

• On Fire! wears off faster when raining.
• Damage over time effects will not deal damage below 10 health, this effect is removed in masochist mode.
• Not attacking will doubles the wear off rate.